Histone H2B Type 2-E (HIST2H2BE) Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Target	Histone H2B Type 2-E (HIST2H2BE)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST2H2BE.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16778 (UniProt, ExPASy)
UniProt Secondary AC	A3KMC7, A8K110, Q4KMY1, Q5QNX0, Q9UE88
UniProt Entry Name	H2B2E_HUMAN
KEGG	hsa:8349
String	9606.ENSP00000358151
Molecular Weight	Calculated MW: 13.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse H2BC21.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone H2B Type 2-E (HIST2H2BE)

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