Histone H2B Type 2-E (HIST2H2BE) Antibody

HIST2H2BE Antibody is a Rabbit Polyclonal antibody against HIST2H2BE. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Target	Histone H2B Type 2-E (HIST2H2BE)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/2000 - 1/10000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of Human Histone H2B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16778 (UniProt, ExPASy)
UniProt Secondary AC	A3KMC7, A8K110, Q4KMY1, Q5QNX0, Q9UE88
UniProt Entry Name	H2B2E_HUMAN
Gene Symbol	HIST2H2BE
GeneID	8349
NCBI Accession	NP_003519.1
KEGG	hsa:8349
String	9606.ENSP00000358151
Molecular Weight	Calculated MW: 14 kDa Observed MW: 17 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Specificity	Expected to show reactivity with HIST2H2BE in a wide range of species.
Concentration	0.44 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone H2B Type 2-E (HIST2H2BE)

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