Histone Cluster 2, H3a (HIST2H3A) Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq].

Target	Histone Cluster 2, H3a (HIST2H3A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q71DI3 (UniProt, ExPASy)
UniProt Secondary AC	A2BDF6, A6NFS4, Q6B053
UniProt Entry Name	H32_HUMAN
Gene Symbol	HIST2H3A
KEGG	hsa:126961 hsa:333932 hsa:653604
String	9606.ENSP00000385479
Molecular Weight	Calculated MW: 15.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Pig, Chicken, Zebrafish, Drosophila, Xenopus and C. elegans H3C15.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone Cluster 2, H3a (HIST2H3A)

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