Histone Cluster 2, H3a (HIST2H3A) Antibody
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Catalogue No: abx031141
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq].
Research Articles on Histone Cluster 2, H3a (HIST2H3A)
| Target | Histone Cluster 2, H3a (HIST2H3A) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q71DI3 (UniProt, ExPASy) |
| UniProt Secondary AC | A2BDF6, A6NFS4, Q6B053 |
| UniProt Entry Name | H32_HUMAN |
| Gene Symbol | HIST2H3A |
| KEGG | hsa:126961 hsa:333932 hsa:653604 |
| String | 9606.ENSP00000385479 |
| Molecular Weight | Calculated MW: 15.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Chicken, Zebrafish, Drosophila, Xenopus and C. elegans H3C15. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |