Histone H3.1t (HIST3H3) Antibody

HIST3H3 is are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.

Target	Histone H3.1t (HIST3H3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST3H3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16695 (UniProt, ExPASy)
UniProt Secondary AC	B2R5K3, Q6FGU4
UniProt Entry Name	H31T_HUMAN
KEGG	hsa:8290
String	9606.ENSP00000355657
Molecular Weight	Calculated MW: 15.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Pig, Chicken, Yeast, Zebrafish, Drosophila, Xenopus and C. elegans H3-4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone H3.1t (HIST3H3)

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