Histone H2A.x (pS139) Antibody

Catalogue No: abx000167
Price: £120.00
(Size: 20 µl)
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Histone H2A.x (pS139) Antibody is a Rabbit Polyclonal antibody against Histone H2A.x (pS139). Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Target Histone H2A.x (pS139)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16104 (UniProt, ExPASy)
UniProt Secondary AC Q4ZGJ7, Q6IAS5
UniProt Entry Name H2AX_HUMAN
Gene Symbol H2AFX
GeneID 3014
KEGG hsa:3014
String 9606.ENSP00000434024
Molecular Weight Calculated MW: 15 kDa
Observed MW: 15 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Histone H2A.x (pS139)

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