Histone H3R2me2a Antibody

Histone H3R2me2a Antibody is a Rabbit Polyclonal antibody against Histone H3R2me2a. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Target	Histone H3R2me2a
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200, ChIP: 1/20 - 1/100, ChIP-seq: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic asymmetric dimethylated peptide around R2 of human histone H3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16695 (UniProt, ExPASy)
UniProt Secondary AC	B2R5K3, Q6FGU4
UniProt Entry Name	H31T_HUMAN
Gene Symbol	HIST3H3
GeneID	8290
NCBI Accession	NP_003520.1
KEGG	hsa:8290
String	9606.ENSP00000355657
Molecular Weight	Calculated MW: 16 kDa Observed MW: 17 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	0.69 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone H3R2me2a

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