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Histone H4K20me2 Antibody
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Catalogue No: abx000018
Price:
£120.00
(Size: 20 µl)
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Histone H4K20me2 Antibody is a Rabbit Polyclonal antibody against Histone H4K20me2. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Research Articles on Histone H4K20me2
| Target | Histone H4K20me2 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP, ChIP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200, ChIP: 1/20 - 1/100, ChIP-seq: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic Peptide. A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P62805 (UniProt, ExPASy) |
| UniProt Secondary AC | A2VCL0, P02304, P02305, Q6DRA9, Q6FGB8, Q6NWP7 |
| UniProt Entry Name | H4_HUMAN |
| Gene Symbol | H4C14 |
| GeneID | 8370 |
| KEGG | hsa:121504 hsa:554313 hsa:8294 hsa:8359 hsa:8360 hsa:8361 hsa:8362 hsa:8363 hsa:8364 hsa:8365 hsa:8366 hsa:8367 hsa:8368 hsa:8370 |
| String | 9606.ENSP00000484789 |
| Molecular Weight | Calculated MW: 11 kDa Observed MW: 13 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
