Histone H4K20me2 Antibody

Catalogue No: abx000018
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
Histone H4K20me2 Antibody is a Rabbit Polyclonal antibody against Histone H4K20me2. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Target Histone H4K20me2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP, ChIP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200, ChIP: 1/20 - 1/100, ChIP-seq: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62805 (UniProt, ExPASy)
UniProt Secondary AC A2VCL0, P02304, P02305, Q6DRA9, Q6FGB8, Q6NWP7
UniProt Entry Name H4_HUMAN
Gene Symbol H4C14
GeneID 8370
KEGG hsa:121504 hsa:554313 hsa:8294 hsa:8359 hsa:8360 hsa:8361 hsa:8362 hsa:8363 hsa:8364 hsa:8365 hsa:8366 hsa:8367 hsa:8368 hsa:8370
String 9606.ENSP00000484789
Molecular Weight Calculated MW: 11 kDa
Observed MW: 13 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Histone H4K20me2

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