Hexokinase 2 (HK2) Antibody

HK2 Antibody is a Rabbit Polyclonal antibody against HK2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Target	Hexokinase 2 (HK2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52789 (UniProt, ExPASy)
UniProt Secondary AC	D6W5J2, Q8WU87, Q9UN82
UniProt Entry Name	HXK2_HUMAN
Gene Symbol	HK2
GeneID	3099
NCBI Accession	NP_000180.2
KEGG	hsa:3099
String	9606.ENSP00000290573
Molecular Weight	Calculated MW: 102 kDa Observed MW: 102 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hexokinase 2 (HK2)

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