HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2) Antibody
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Catalogue No: abx031442
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq].
Research Articles on HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2)
| Target | HLA Class II Histocompatibility Antigen, DQ Alpha 2 Chain (HLA-DQA2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01906 (UniProt, ExPASy) |
| UniProt Secondary AC | A2BF37, B0V0E7, O19789, Q5SQ94, Q5SR04 |
| UniProt Entry Name | DQA2_HUMAN |
| Gene Symbol | HLA-DQA2 |
| GeneID | 3118 |
| OMIM | 613503 |
| NCBI Accession | NP_064440.1 |
| HGNC | 4943 |
| KEGG | hsa:3118 |
| Ensembl | ENSG00000206301 |
| String | 9606.ENSP00000364076 |
| Molecular Weight | Calculated MW: 28 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |