Menu

HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) Antibody

Catalogue No: abx001330
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) Antibody

Available Options

* Size:




HLA-DRA Antibody is a Rabbit Polyclonal antibody against HLA-DRA. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008].

Target HLA-DRA
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human HLA-DRA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01903 (UniProt, ExPASy)
UniProt Secondary AC A2BET4, Q30160, Q6IAZ1, Q861I2, Q9TP70
UniProt Entry Name DRA_HUMAN
Gene Symbol HLA-DRA
GeneID 3122
KEGG hsa:3122
String 9606.ENSP00000378786
Molecular Weight Calculated MW: 28 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good