HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA) Antibody

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Catalogue No: abx001330
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
HLA-DRA Antibody is a Rabbit Polyclonal antibody against HLA-DRA. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008].

Target HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 26-216 of human HLA-DRA.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01903 (UniProt, ExPASy)
UniProt Secondary AC A2BET4, Q30160, Q6IAZ1, Q861I2, Q9TP70
UniProt Entry Name DRA_HUMAN
Gene Symbol HLA-DRA
GeneID 3122
NCBI Accession NP_061984.2
KEGG hsa:3122
String 9606.ENSP00000378786
Molecular Weight Calculated MW: 29 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on HLA Class II Histocompatibility Antigen, DR Alpha Chain (HLA-DRA)


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