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| Target | Major Histocompatibility Complex Class I E (HLA-E) |
| Clonality | Monoclonal |
| Clone | Q331 |
| Reactivity | Human |
| Tested Applications | IHC, FCM, IP |
| Host | Mouse |
| Recommended dilutions | Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Biotin |
| Immunogen | Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide. |
| Isotype | IgG1 |
| Storage | Store at 2-8°C. Do not freeze. |
| UniProt Primary AC | P13747 (UniProt, ExPASy) |
| Gene Symbol | HLA-E |
| GeneID | 3133 |
| KEGG | hsa:3133 |
| String | 9606.ENSP00000365817 |
| Buffer | PBS solution with 15 mM sodium azide. |
| Specificity | The antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that the antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly). |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |