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Porphobilinogen Deaminase (HMBS) Antibody

Catalogue No: abx001474
Price: £120.00
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Porphobilinogen Deaminase (HMBS) Antibody

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HMBS Antibody is a Rabbit Polyclonal antibody against HMBS. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Target HMBS
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human HMBS.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08397 (UniProt, ExPASy)
UniProt Secondary AC A8K2L0, G3V1P4, G5EA58, P08396, Q16012
UniProt Entry Name HEM3_HUMAN
Gene Symbol HMBS
GeneID 3145
KEGG hsa:3145
String 9606.ENSP00000278715
Molecular Weight Calculated MW: 33 kDa, 34 kDa, 37 kDa, 39 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Porphobilinogen Deaminase (HMBS) Antibody

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