High Mobility Group Protein HMG-I/HMG-Y (HMGA1) Antibody
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Catalogue No: abx034227
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US$326.25
(Size: 80 µl)
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Datasheet SDS
HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.
Research Articles on High Mobility Group Protein HMG-I/HMG-Y (HMGA1)
| Target | High Mobility Group Protein HMG-I/HMG-Y (HMGA1) |
| Research Area | Signal Transduction, Metabolic Pathways, Tumor Immunity, Developmental Science, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 64-93 amino acids from the C-terminal region of human HMGA1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P17096 (UniProt, ExPASy) |
| UniProt Secondary AC | P10910, Q5T6U9, Q9UKB0 |
| UniProt Entry Name | HMGA1_HUMAN |
| NCBI Accession | NP_002122.1 NP_665906.1 NP_665908.1 NP_665909.1 NP_665910.1 NP_665912.1 |
| KEGG | hsa:3159 |
| String | 9606.ENSP00000399888 |
| Molecular Weight | Calculated MW: 11.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Hamster HMGA1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |