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High Mobility Group Protein HMGI-C (HMGA2) Antibody

Catalogue No: abx002163
Price: £120.00
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High Mobility Group Protein HMGI-C (HMGA2) Antibody High Mobility Group Protein HMGI-C (HMGA2) Antibody High Mobility Group Protein HMGI-C (HMGA2) Antibody High Mobility Group Protein HMGI-C (HMGA2) Antibody

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HMGA2 Antibody is a Rabbit Polyclonal antibody against HMGA2. This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target HMGA2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human HMGA2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52926 (UniProt, ExPASy)
UniProt Secondary AC E7EP85, E7EWA2, Q1M182, Q1M185, Q1M186, Q1M187, Q1M188
UniProt Entry Name HMGA2_HUMAN
Gene Symbol HMGA2
GeneID 8091
KEGG hsa:8091
String 9606.ENSP00000437621
Molecular Weight Calculated MW: 9 kDa, 10 kDa, 11 kDa
Observed MW: 13 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on High Mobility Group Protein HMGI-C (HMGA2) Antibody

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