High Mobility Group Protein B2 (HMGB2) Antibody
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Catalogue No: abx033220
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.
Research Articles on High Mobility Group Protein B2 (HMGB2)
| Target | High Mobility Group Protein B2 (HMGB2) |
| Research Area | Signal Transduction, Tumor Immunity, Developmental Science, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 92-118 amino acids from the Central region of human HMGB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P26583 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4K8, D3DP37, Q5U072 |
| UniProt Entry Name | HMGB2_HUMAN |
| NCBI Accession | NP_001124160.1 NP_001124161.1 NP_002120.1 |
| KEGG | hsa:3148 |
| String | 9606.ENSP00000296503 |
| Molecular Weight | Calculated MW: 24 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Cow and Pig HMGB2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |