Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL) Antibody
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Catalogue No: abx028671
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US$326.25
(Size: 80 µl)
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Datasheet SDS
HMGCL belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL)
| Target | Hydroxymethylglutaryl-CoA Lyase, Mitochondrial (HMGCL) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 161-190 amino acids from the Central region of human HMGCL. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35914 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DUP4, B7UCC6, D3Y5K7, Q6IBC0, Q96FP8 |
| UniProt Entry Name | HMGCL_HUMAN |
| Gene Symbol | HMGCL |
| KEGG | hsa:3155 |
| String | 9606.ENSP00000363614 |
| Molecular Weight | Calculated MW: 34.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Monkey HMGCL. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |