Hepatocyte Nuclear Factor 4 Alpha (HNF4A) Antibody

HNF4A Antibody is a Rabbit Polyclonal antibody against HNF4A. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Target	Hepatocyte Nuclear Factor 4 Alpha (HNF4A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 226-325 of human HNF4A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41235 (UniProt, ExPASy)
UniProt Entry Name	HNF4A_HUMAN
Gene Symbol	HNF4A
GeneID	3172
NCBI Accession	NP_000448.3
KEGG	hsa:3172
String	9606.ENSP00000312987
Molecular Weight	Calculated MW: 53 kDa Observed MW: 52 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	0.81 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hepatocyte Nuclear Factor 4 Alpha (HNF4A)

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