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Histamine N-Methyltransferase (HNMT) Antibody

Catalogue No: abx001961
Price: £120.00
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Histamine N-Methyltransferase (HNMT) Antibody Histamine N-Methyltransferase (HNMT) Antibody Histamine N-Methyltransferase (HNMT) Antibody

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HNMT Antibody is a Rabbit Polyclonal antibody against HNMT. In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Target HNMT
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human HNMT.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P50135 (UniProt, ExPASy)
UniProt Secondary AC B2R9J3, Q546Z6, Q7Z7I2, Q8IU56, Q8WW98, Q9BRW6
UniProt Entry Name HNMT_HUMAN
Gene Symbol HNMT
GeneID 3176
KEGG hsa:3176
String 9606.ENSP00000280097
Molecular Weight Calculated MW: 6 kDa, 14 kDa, 33 kDa
Observed MW: 34 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Histamine N-Methyltransferase (HNMT) Antibody

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