Heterogeneous Nuclear Ribonucleoprotein H2 (HNRNPH2) Antibody

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein.

Target	Heterogeneous Nuclear Ribonucleoprotein H2 (HNRNPH2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human HNRNPH2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55795 (UniProt, ExPASy)
UniProt Secondary AC	A1L400, Q9HHA7
UniProt Entry Name	HNRH2_HUMAN
KEGG	hsa:3188
String	9606.ENSP00000361927
Molecular Weight	Calculated MW: 49.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Cow HNRNPH2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Heterogeneous Nuclear Ribonucleoprotein H2 (HNRNPH2)

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