Homeobox Protein Hox-D10 (HOXD10) Antibody

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Target	Homeobox Protein Hox-D10 (HOXD10)
Clonality	Polyclonal
Reactivity	Mouse, Zebrafish
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human HOXD10.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P28358 (UniProt, ExPASy)
UniProt Secondary AC	Q6NT10
UniProt Entry Name	HXD10_HUMAN
Gene Symbol	HOXD10
KEGG	hsa:3236
String	9606.ENSP00000249501
Molecular Weight	Calculated MW: 38.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Chicken HOXD10.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Homeobox Protein Hox-D10 (HOXD10)

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