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4-Hydroxyphenylpyruvate Dioxygenase (HPDL) Antibody
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Catalogue No: abx004989
Price:
US$203.00
(Size: 20 µl)
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HPDL Antibody is a Rabbit Polyclonal antibody against HPDL. The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on 4-Hydroxyphenylpyruvate Dioxygenase (HPDL)
| Target | 4-Hydroxyphenylpyruvate Dioxygenase (HPDL) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human HPD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P32754 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K461, B3KQ63, Q13234 |
| UniProt Entry Name | HPPD_HUMAN |
| Gene Symbol | HPDL |
| GeneID | 3242 |
| NCBI Accession | NP_002141.1 |
| KEGG | hsa:3242 |
| String | 9606.ENSP00000289004 |
| Molecular Weight | Calculated MW: 45 kDa Observed MW: 45 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.246 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
