Hydroxysteroid 17-Beta Dehydrogenase 10 (HSD17B10) Antibody

HSD17B10 Antibody is a Rabbit Polyclonal antibody against HSD17B10. This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Target	Hydroxysteroid 17-Beta Dehydrogenase 10 (HSD17B10)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human ERAB/ERAB/HSD17B10.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99714 (UniProt, ExPASy)
UniProt Secondary AC	Q5H927, Q6IBS9, Q8TCV9, Q96HD5
Gene Symbol	HSD17B10
GeneID	3028
NCBI Accession	NP_004484.1
Molecular Weight	Calculated MW: 27 kDa Observed MW: 27 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hydroxysteroid 17-Beta Dehydrogenase 10 (HSD17B10)

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