Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody

HSD17B4 Antibody is a Rabbit Polyclonal antibody against HSD17B4. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target	Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human HSD17B4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51659 (UniProt, ExPASy)
UniProt Secondary AC	B4DNV1, B4DVS5, E9PB82, F5HE57
UniProt Entry Name	DHB4_HUMAN
Gene Symbol	HSD17B4
GeneID	3295
NCBI Accession	NP_000405.1
KEGG	hsa:3295
String	9606.ENSP00000420914
Molecular Weight	Calculated MW: 80 kDa Observed MW: 88 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4)

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