3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1) Antibody
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Catalogue No: abx028161
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(Size: 80 µl)
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Datasheet SDS
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5) ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta, 17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta, 17 beta-diol to 5-alpha-dihydrotestosterone.
Research Articles on 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1)
| Target | 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 1 (HSD3B1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human HSD3B1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P14060 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K691, Q14545, Q8IV65 |
| UniProt Entry Name | 3BHS1_HUMAN |
| Gene Symbol | HSD3B1 |
| GeneID | 3283 |
| OMIM | 109715 |
| HGNC | 5217 |
| KEGG | hsa:3283 |
| Ensembl | ENSG00000203857 |
| String | 9606.ENSP00000358421 |
| Molecular Weight | Calculated MW: 42.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |