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HSF1 Sumoylation Site Antibody
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Catalogue No: abx031603
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.
Research Articles on HSF1 Sumoylation Site
| Target | HSF1 Sumoylation Site |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 278-309 amino acids from human HSF1 Sumoylation Site. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q00613 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4L0, A8MW26, Q53XT4 |
| UniProt Entry Name | HSF1_HUMAN |
| GeneID | 3297 |
| NCBI Accession | NP_005517.1 |
| KEGG | hsa:3297 |
| String | 9606.ENSP00000431512 |
| Molecular Weight | Calculated MW: 57.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow HSF1. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |