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Heat Shock Protein Beta 8 (HSPB8) Antibody

Catalogue No: abx001956
Price: £120.00
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Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody Heat Shock Protein Beta 8 (HSPB8) Antibody

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HSPB8 Antibody is a Rabbit Polyclonal antibody against HSPB8. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Target HSPB8
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human HSPB8.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UJY1 (UniProt, ExPASy)
UniProt Secondary AC B2R6A6, Q6FIH3, Q9UKS3
UniProt Entry Name HSPB8_HUMAN
Gene Symbol HSPB8
GeneID 26353
String 9606.ENSP00000281938
Molecular Weight Calculated MW: 21 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Heat Shock Protein Beta 8 (HSPB8) Antibody

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