5-Hydroxytryptamine Receptor 2B (HTR2B) Antibody

HTR2B Antibody is a Rabbit Polyclonal antibody against HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Target	5-Hydroxytryptamine Receptor 2B (HTR2B)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41595 (UniProt, ExPASy)
UniProt Secondary AC	B2R9D5, Q53TI1, Q62221, Q6P523
UniProt Entry Name	5HT2B_HUMAN
Gene Symbol	HTR2B
GeneID	3357
NCBI Accession	NP_000858.3
KEGG	hsa:3357
String	9606.ENSP00000258400
Molecular Weight	Calculated MW: 54 kDa Observed MW: 47 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	2.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 5-Hydroxytryptamine Receptor 2B (HTR2B)

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