Human Aquaporin 4 (AQP4) ELISA Kit

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Catalogue No: abx573238
Price: US$681.50
(Size: 96 tests)

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Human Aquaporin 4 (AQP4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aquaporin 4 (AQP4) concentrations in tissue homogenates, cell lysates and other biological fluids.

Introduction Aquaporin-4, also known as AQP4, is a water channel protein encoded by the AQP4 gene in humans. Aquaporin-4’s overall function is to provide fast water transportation as well as maintain homeostatic balance within the central nervous system. It is the primary water channel protein that reconciles the homeostasis of water in the CNS. AQP4 may be involved in a variety of physiological processes such as waste removal and fine-tuning of potassium homeostasis. Water flowing into and out of the brain or spinal cord is assisted by AQP4. Here, AQP4 channels respond passively to osmotic gradients. In addition, they play a role in brain water transport, cell migration, brain edema, metabolism and cell homeostasis.
Target Aquaporin 4 (AQP4)
Reactivity Human
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
UniProt Primary AC P55087 (UniProt, ExPASy)
UniProt Secondary AC P78564
UniProt Entry Name AQP4_HUMAN
Gene Symbol AQP4
GeneID 361
OMIM 600308
HGNC 637
KEGG hsa:361
Ensembl ENSG00000171885
String 9606.ENSP00000372654
Test Range 0.625 ng/ml - 40 ng/ml
Sensitivity < 0.245 ng/ml
Standard Form Lyophilized
Detection Method Colorimetric
Assay Type Sandwich
Assay Data Quantitative
Sample Type Tissue homogenates, cell lysates and other biological fluids.
Availability Shipped within 5-12 working days.
Note This product is for research use only.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Standard 40 ng/ml
Research Articles on Aquaporin 4 (AQP4)


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