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Introduction | Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. It is a tissue-specific subtype of troponin I, which in turn is a part of the troponin complex. The TNNI3 gene encoding cardiac troponin I (cTnI) is located at 19q13.4 in the human chromosomal genome. Human cTnI is a 24 kDa protein consisting of 210 amino acids with isoelectric point (pI) of 9.87. cTnI is exclusively expressed in adult cardiac muscle. |
Target | Troponin I, Cardiac Muscle (TNNI3) |
Reactivity | Human |
Tested Applications | CLIA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | The validity for this kit is 6 months. |
Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
UniProt Primary AC | P19429 (UniProt, ExPASy) |
UniProt Entry Name | TNNI3_HUMAN |
Gene Symbol | TNNI3 |
GeneID | 7137 |
OMIM | 115210 |
NCBI Accession | NP_000354.4 NM_000363.4 |
HGNC | 11947 |
KEGG | hsa:7137 |
Ensembl | ENST00000344887, ENSP00000341838, ENSG00000129991 |
String | 9606.ENSP00000341838 |
Test Range | 78 pg/ml - 5000 pg/ml |
Sensitivity | 46.9 pg/ml |
Standard Form | Lyophilized |
Detection Method | Chemiluminescent |
Assay Type | Sandwich |
Assay Data | Quantitative |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-12 working days. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Plate coated with | Antibody |