Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit

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Catalogue No: abx384944
Price: US$797.50
(Size: 96 tests)

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This product is currently under production. The lead time for this product may be several months. Please contact us at [email protected] for the lead time before purchasing this product.

Human MAS Related GPR Member X2 (MRGPRX2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MAS Related GPR Member X2 (MRGPRX2) concentrations in Tissue homogenates, cell lysates and other biological fluids.

Introduction Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene. MRGPRX2 recognises and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. Activation in response to these compounds results in mast cell degranulation with subsequent pseudo-allergic reactions, characterised by histamine release, inflammation and airway contraction.
Target MAS Related GPR Member X2 (MRGPRX2)
Reactivity Human
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
UniProt Primary AC Q96LB1 (UniProt, ExPASy)
UniProt Entry Name MRGX2_HUMAN
Gene Symbol MRGPRX2
GeneID 117194
OMIM 607228
HGNC 17983
KEGG hsa:117194
Ensembl ENSG00000183695
String 9606.ENSP00000333800
Test Range 0.156 ng/ml - 10 ng/ml
Sensitivity < 0.06 ng/ml
Standard Form Lyophilized
Detection Method Colorimetric
Assay Type Sandwich
Assay Data Quantitative
Sample Type Tissue homogenates, cell lysates and other biological fluids.
Availability Please enquire.
Note This product is for research use only.

The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.

Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Standard 100 ng/ml
Intra Assay CV ≤ 5.3%
Inter Assay CV ≤ 7.9%
Research Articles on MAS Related GPR Member X2 (MRGPRX2)


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