Human Proteasome Subunit Alpha Type 2 (PSMA2) ELISA Kit
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Catalogue No: abx382503
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US$797.50
(Size: 96 tests)
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Human Proteasome Subunit Alpha Type 2 (PSMA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Alpha Type 2 (PSMA2) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Research Articles on Proteasome Subunit Alpha Type 2 (PSMA2)
| Introduction | Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S proteasome complex. |
| Target | Proteasome Subunit Alpha Type 2 (PSMA2) |
| Reactivity | Human |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Shelf Life | 6 months. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| UniProt Primary AC | P25787 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6ICS6, Q9BU45 |
| UniProt Entry Name | PSA2_HUMAN |
| Gene Symbol | PSMA2 |
| GeneID | 5683 |
| OMIM | 176842 |
| HGNC | 9531 |
| KEGG | hsa:5683 |
| Ensembl | ENSG00000106588 |
| String | 9606.ENSP00000223321 |
| Test Range | 0.78 ng/ml - 50 ng/ml |
| Sensitivity | < 0.4 ng/ml |
| Standard Form | Lyophilized |
| Detection Method | Colorimetric |
| Assay Type | Sandwich |
| Assay Data | Quantitative |
| Sample Type | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Standard | 10 ng/ml |