Human Proteasome Subunit Alpha Type 2 (PSMA2) ELISA Kit

Human Proteasome Subunit Alpha Type 2 (PSMA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Proteasome Subunit Alpha Type 2 (PSMA2) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.

Introduction	Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. This protein is one of the 17 essential subunits (alpha subunits 1-7, constitutive beta subunits 1-7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S proteasome complex.
Target	Proteasome Subunit Alpha Type 2 (PSMA2)
Reactivity	Human
Tested Applications	ELISA
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Storage	Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Validity	The validity for this kit is 6 months.
Stability	The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.
UniProt Primary AC	P25787 (UniProt, ExPASy)
UniProt Secondary AC	Q6ICS6, Q9BU45
UniProt Entry Name	PSA2_HUMAN
Gene Symbol	PSMA2
GeneID	5683
OMIM	176842
HGNC	9531
KEGG	hsa:5683
Ensembl	ENSG00000106588
String	9606.ENSP00000223321
Test Range	0.78 ng/ml - 50 ng/ml
Sensitivity	< 0.4 ng/ml
Standard Form	Lyophilized
Detection Method	Colorimetric
Assay Type	Sandwich
Assay Data	Quantitative
Sample Type	Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability	Shipped within 5-15 working days.
Note	This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Standard	10 ng/ml

Research Articles on Proteasome Subunit Alpha Type 2 (PSMA2)

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