Human Survival Of Motor Neuron 2, Centromeric (SMN2) Protein

Catalogue No: abx650336
Price: £170.00
(Size: 10 µg)
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Human SMN2 Protein is a recombinant Human protein produced in E. coli using Prokaryotic expression.

Target Survival Of Motor Neuron 2, Centromeric (SMN2)
Origin Human
Expression Recombinant
Tested Applications WB, SDS-PAGE
Host E. coli
Conjugation Unconjugated
Form Lyophilized
Purity > 95%
Reconstitution Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Storage Store at 2-8 °C for up to one month. Aliquot and store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q16637 (UniProt, ExPASy)
UniProt Secondary AC A8K0V4, Q13119, Q549U5, Q96J51
UniProt Entry Name SMN_HUMAN
KEGG hsa:6606 hsa:6607
String 9606.ENSP00000370119
Molecular Weight Calculated MW: 29.3 kDa
Observed MW (SDS-PAGE): 33 kDa

Possible reasons why the actual band size differs from the predicted band size:
1. Splice variants. Alternative splicing may create different sized proteins from the same gene.
2. Relative charge. The composition of amino acids may affect the charge of the protein.
3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size.
4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form.
5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed.
Sequence Fragment Glu16-Pro251
Sequence EDSVL FRRGTGQSDD SDIWDDTALI KAYDKAVASF KHALKNGDIC ETSGKPKTTP KRKPAKKNKS QKKNTAASLQ QWKVGDKCSA IWSEDGCIYP ATIASIDFKR ETCVVVYTGY GNREEQNLSD LLSPICEVAN NIEQNAQENE NESQVSTDES ENSRSPGNKS DNIKPKSAPW NSFLPPPPPM PGPRLGPGKP GLKFNGPPPP PPPPPPHLLS CWLPPFPSGP PIIPPPPPIC P
Tag N-terminal His tag
Buffer Prior to lyophilization: 100 mM NaHCO3, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl, 5% Trehalose.
Activity Not tested
Concentration Prior to lyophilization: 200 µg/ml
Availability Shipped within 5-7 working days.
Note This product is for research use only.

Not for human consumption, cosmetic, therapeutic or diagnostic use.
Research Articles on Survival Of Motor Neuron 2, Centromeric (SMN2)

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