Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody

Catalogue No: abx000524
Price: £185.00
(Size: 20 µl)

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Datasheet SDS
HIF1a Antibody is a Rabbit Monoclonal antibody against HIF1a. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Target HIF1a
Clonality Monoclonal
Clone A927
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of Human HIF-1 alpha.
Isotype IgG
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q16665 (UniProt, ExPASy)
UniProt Secondary AC C0LZJ3, Q53XP6, Q96PT9, Q9UPB1
Gene Symbol HIF1A
GeneID 3091
Molecular Weight Calculated MW: 82 kDa, 92 kDa, 95 kDa
Observed MW: 120 kDa
Buffer PBS, pH 7.3 with 0.05% Proclin-300, 0.05% BSA, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on HIF1a

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