Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody

HIF1a Antibody is a Rabbit Monoclonal antibody against HIF1a. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Target	Hypoxia Inducible Factor 1 Alpha (HIF1a)
Clonality	Monoclonal
Clone	A927
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human HIF1α.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16665 (UniProt, ExPASy)
UniProt Secondary AC	C0LZJ3, Q53XP6, Q96PT9, Q9UPB1
Gene Symbol	HIF1A
GeneID	3091
NCBI Accession	NP_001521.1
Molecular Weight	Calculated MW: 93 kDa Observed MW: 120 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 0.05% BSA, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hypoxia Inducible Factor 1 Alpha (HIF1a)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue