Hypoxia Inducible Factor 1 Alpha (HIF1a) Antibody
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Catalogue No: abx000524
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US$232.00
(Size: 20 µl)
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Datasheet SDS
HIF1a Antibody is a Rabbit Monoclonal antibody against HIF1a. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Research Articles on Hypoxia Inducible Factor 1 Alpha (HIF1a)
| Target | Hypoxia Inducible Factor 1 Alpha (HIF1a) |
| Research Area | Tumor Immunity, Cardiovascular Biology, Reproductive Science, Cancer |
| Clonality | Monoclonal |
| Clone | A927 |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human HIF1α. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16665 (UniProt, ExPASy) |
| UniProt Secondary AC | C0LZJ3, Q53XP6, Q96PT9, Q9UPB1 |
| Gene Symbol | HIF1A |
| GeneID | 3091 |
| NCBI Accession | NP_001521.1 |
| Molecular Weight | Calculated MW: 93 kDa Observed MW: 120 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 0.05% BSA, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |