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Islet Amyloid Polypeptide (IAPP) Antibody

Catalogue No: abx002102
Price: £120.00
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Islet Amyloid Polypeptide (IAPP) Antibody

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IAPP Antibody is a Rabbit Polyclonal antibody against IAPP. Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Target IAPP
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human IAPP.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10997 (UniProt, ExPASy)
UniProt Secondary AC Q0ZD87, Q14598
UniProt Entry Name IAPP_HUMAN
Gene Symbol IAPP
GeneID 3375
KEGG hsa:3375
String 9606.ENSP00000240652
Molecular Weight Calculated MW: 9 kDa
Observed MW: 10 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Islet Amyloid Polypeptide (IAPP) Antibody

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