Intercellular Adhesion Molecule 3 (ICAM3) Antibody

ICAM3 Antibody is a Rabbit Polyclonal antibody against ICAM3. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.

Target	Intercellular Adhesion Molecule 3 (ICAM3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 270-490 of human ICAM3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P32942 (UniProt, ExPASy)
UniProt Secondary AC	Q6PD68
UniProt Entry Name	ICAM3_HUMAN
Gene Symbol	ICAM3
GeneID	3385
NCBI Accession	NP_002153.2
KEGG	hsa:3385
String	9606.ENSP00000160262
Molecular Weight	Calculated MW: 60 kDa Observed MW: 140 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Intercellular Adhesion Molecule 3 (ICAM3)

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