Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody

IFIH1 Antibody is a Rabbit Polyclonal antibody against IFIH1. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.

Target	Interferon Induced With Helicase C Domain 1 (IFIH1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human IFIH1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BYX4 (UniProt, ExPASy)
UniProt Secondary AC	Q2NKL6, Q6DC96, Q86X56, Q96MX8, Q9H3G6
UniProt Entry Name	IFIH1_HUMAN
Gene Symbol	IFIH1
GeneID	64135
NCBI Accession	NP_071451.2
String	9606.ENSP00000263642
Molecular Weight	Calculated MW: 117 kDa Observed MW: 117 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	0.75 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon Induced With Helicase C Domain 1 (IFIH1)

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