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Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody

Catalogue No: abx001815
Price: £120.00
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Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody

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IFIH1 Antibody is a Rabbit Polyclonal antibody against IFIH1. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.

Target IFIH1
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IFIH1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9BYX4 (UniProt, ExPASy)
UniProt Secondary AC Q2NKL6, Q6DC96, Q86X56, Q96MX8, Q9H3G6
UniProt Entry Name IFIH1_HUMAN
Gene Symbol IFIH1
GeneID 64135
String 9606.ENSP00000263642
Molecular Weight Calculated MW: 25 kDa, 116 kDa
Observed MW: Refer to figures
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 0.75 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interferon Induced With Helicase C Domain 1 (IFIH1) Antibody

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