Interferon Gamma (IFNG) Antibody

Catalogue No: abx011002
Price: £290.00
(Size: 100 µl)
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Interferon gamma (IFN gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon gamma through the activation of transcription factor NFKB.

Target IFN gamma
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human IFN-gamma expressed in E. Coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01579 (UniProt, ExPASy)
UniProt Secondary AC B5BU88, Q53ZV4
UniProt Entry Name IFNG_HUMAN
Gene Symbol IFNG
GeneID 3458
OMIM 147570
HGNC 5438
KEGG hsa:3458
Ensembl ENSG00000111537
String 9606.ENSP00000229135
Molecular Weight 19 kDa
Buffer PBS, containing 0.03% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on IFN gamma

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