IGF1R (pY1161) Antibody

IGF1R (pY1161) Antibody is a Rabbit Polyclonal antibody against IGF1R (pY1161). This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Target	IGF1R (pY1161)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y1161 of human IGF1R.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08069 (UniProt, ExPASy)
UniProt Secondary AC	B1B5Y2, Q14CV2, Q9UCC0
UniProt Entry Name	IGF1R_HUMAN
Gene Symbol	IGF1R
GeneID	3480
NCBI Accession	NP_000866.1
KEGG	hsa:3480
String	9606.ENSP00000268035
Molecular Weight	Calculated MW: 155 kDa Observed MW: 95 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on IGF1R (pY1161)

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