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IGF1R (pY1280) Antibody

Catalogue No: abx000416
Price: £220.00
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IGF1R (pY1280) Antibody

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IGF1R (pY1280) Antibody is a Rabbit Polyclonal antibody against IGF1R (pY1280). This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.

Target IGF1R (pY1280)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1280 of human IGF1R.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08069 (UniProt, ExPASy)
UniProt Secondary AC B1B5Y2, Q14CV2, Q9UCC0
UniProt Entry Name IGF1R_HUMAN
Gene Symbol IGF1R
GeneID 3480
KEGG hsa:3480
String 9606.ENSP00000268035
Molecular Weight Calculated MW: 154 kDa
Observed MW: 95 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on IGF1R (pY1280) Antibody

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