Interleukin 10 (IL10) Antibody
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Catalogue No: abx011006
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF- kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Research Articles on Interleukin 10 (IL10)
| Target | Interleukin 10 (IL10) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Immunology |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human IL-10 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P22301 (UniProt, ExPASy) |
| UniProt Entry Name | IL10_HUMAN |
| Gene Symbol | IL10 |
| GeneID | 3586 |
| OMIM | 124092 |
| HGNC | 5962 |
| KEGG | hsa:3586 |
| Ensembl | ENSG00000136634 |
| String | 9606.ENSP00000412237 |
| Molecular Weight | 21 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |