Interleukin 17A (IL17A) Antibody (APC)

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Catalogue No: abx229359
Price: US$217.50
(Size: 20 tests)

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Flow cytometry analysis of HEK293T cells transiently transfected with a pcDNA3.1 plasmid encoding the Human Interleukin 17A (IL17A) gene using APC-conjugated Interleukin 17A (IL17A) Antibody (gray histogram) and an APC-conjugated Mouse IgG1 Kappa lsotype Control Antibody (black histogram).
Interleukin 17A (IL17A) Antibody (APC) Interleukin 17A (IL17A) Antibody (APC)

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Datasheet SDS
Interleukin 17A (IL17A) Antibody (APC) is a Human Monoclonal Antibody against Interleukin 17A (IL17A).

Interleukin 17A (IL17A) is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A is secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts. The enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kB and costimulation of T cell proliferation. Activated IL-17-secreting CD4+ helper T cells (Th17 cells) can mediate autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to Rat IL-17A, Mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS).

Target Interleukin 17A (IL17A)
Research Area Infection Immunity
Clonality Monoclonal
Clone L803
Reactivity Human
Tested Applications FCM
Host Mouse
Recommended dilutions FCM: 5 μl per test (1 million cells in 100 μl sample volume or per 100 μl of whole blood). Optimal dilutions/concentrations should be determined by the end user.
Conjugation APC
Excitation/Emission 651/660
Laser Line 647
Isotype IgG1 Kappa
Storage Aliquot and store at 2°C to 8°C. Avoid exposure to light. Do not freeze.
Shelf Life 24 months.
UniProt Primary AC Q16552 (UniProt, ExPASy)
GeneID 3605
Buffer PBS, pH 7.2, containing 0.09% stabilizer.
Availability Shipped within 5-15 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Interleukin 17A (IL17A)


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