Interleukin 1 Alpha (IL1A) Antibody
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Catalogue No: abx011004
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Interleukin-1 alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Research Articles on Interleukin 1 Alpha (IL1A)
| Target | Interleukin 1 Alpha (IL1A) |
| Research Area | Cytokines, Apoptosis |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human IL1a expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01583 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53QF9, Q7RU02 |
| Gene Symbol | IL1A |
| GeneID | 3552 |
| OMIM | 147760 |
| HGNC | 5991 |
| KEGG | hsa:3552 |
| Ensembl | ENSG00000115008 |
| String | 9606.ENSP00000263339 |
| Molecular Weight | 30.6 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |