Interleukin 1 Alpha (IL1A) Antibody

Interleukin-1 alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Target	Interleukin 1 Alpha (IL1A)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human IL1a expressed in E. coli.
Isotype	IgG2a
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01583 (UniProt, ExPASy)
UniProt Secondary AC	Q53QF9, Q7RU02
Gene Symbol	IL1A
GeneID	3552
OMIM	147760
HGNC	5991
KEGG	hsa:3552
Ensembl	ENSG00000115008
String	9606.ENSP00000263339
Molecular Weight	30.6 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 1 Alpha (IL1A)

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