Interleukin 10 Receptor Alpha (IL10RA) Antibody

IL10RA Antibody is a Rabbit Polyclonal antibody against IL10RA. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].

Target	Interleukin 10 Receptor Alpha (IL10RA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 265-410 of human IL10RA..
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13651 (UniProt, ExPASy)
UniProt Secondary AC	A8K6I0, B0YJ27
UniProt Entry Name	I10R1_HUMAN
Gene Symbol	IL10RA
GeneID	3587
NCBI Accession	NP_001549.2
KEGG	hsa:3587
String	9606.ENSP00000227752
Molecular Weight	Calculated MW: 63 kDa Observed MW: 90-110 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	1.57 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 10 Receptor Alpha (IL10RA)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue