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Interleukin 13 (IL13) Antibody

Catalogue No: abx001701
Price: £120.00
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Interleukin 13 (IL13) Antibody Interleukin 13 (IL13) Antibody Interleukin 13 (IL13) Antibody Interleukin 13 (IL13) Antibody

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IL13 Antibody is a Rabbit Polyclonal antibody against IL13. This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Target IL13
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-146 of human IL13 (NP_002179.2).
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35225 (UniProt, ExPASy)
UniProt Secondary AC O43644, Q4VB52, Q9UDC7
UniProt Entry Name IL13_HUMAN
Gene Symbol IL13
GeneID 3596
KEGG hsa:3596
String 9606.ENSP00000304915
Molecular Weight Calculated MW: 15 kDa
Observed MW: 16 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 2.59 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interleukin 13 (IL13) Antibody

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