Interleukin 17A (IL17A) Antibody

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Target	Interleukin 17A (IL17A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 61-87 amino acids from the Central region of human IL17A.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16552 (UniProt, ExPASy)
UniProt Secondary AC	Q5T2P0
UniProt Entry Name	IL17_HUMAN
KEGG	hsa:3605
String	9606.ENSP00000344192
Molecular Weight	Calculated MW: 17.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow IL17A.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 17A (IL17A)

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