Interleukin 17A (IL17A) Antibody

IL17A Antibody is a Rabbit Polyclonal antibody against IL17A. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Target	Interleukin 17A (IL17A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16552 (UniProt, ExPASy)
UniProt Secondary AC	Q5T2P0
UniProt Entry Name	IL17_HUMAN
Gene Symbol	IL17A
GeneID	3605
NCBI Accession	NP_002181.1
KEGG	hsa:3605
String	9606.ENSP00000344192
Molecular Weight	Calculated MW: 18 kDa Observed MW: 18-25 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 17A (IL17A)

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