Interleukin 17A (IL17A) Antibody
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Catalogue No: abx000823
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US$217.50
(Size: 20 µl)
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Datasheet SDS
IL17A Antibody is a Rabbit Polyclonal antibody against IL17A. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Research Articles on Interleukin 17A (IL17A)
| Target | Interleukin 17A (IL17A) |
| Research Area | Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16552 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5T2P0 |
| UniProt Entry Name | IL17_HUMAN |
| Gene Symbol | IL17A |
| GeneID | 3605 |
| NCBI Accession | NP_002181.1 |
| KEGG | hsa:3605 |
| String | 9606.ENSP00000344192 |
| Molecular Weight | Calculated MW: 18 kDa Observed MW: 18-25 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |