Interleukin 1 Beta (IL1B) Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Target	Interleukin 1 Beta (IL1B)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human IL1B expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01584 (UniProt, ExPASy)
UniProt Secondary AC	Q53X59, Q53XX2, Q7M4S7, Q7RU01, Q96HE5, Q9UCT6
UniProt Entry Name	IL1B_HUMAN
Gene Symbol	IL1B
GeneID	3553
OMIM	147720
HGNC	5992
KEGG	hsa:3553
Ensembl	ENSG00000125538
String	9606.ENSP00000263341
Molecular Weight	31 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 1 Beta (IL1B)

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