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Interleukin 1 Beta (IL1B) Antibody

Catalogue No: abx001029
Price: £120.00
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IL1B Antibody is a Rabbit Polyclonal antibody against IL1B. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Target IL1B
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IL1B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01584 (UniProt, ExPASy)
UniProt Secondary AC Q53X59, Q53XX2, Q7M4S7, Q7RU01, Q96HE5, Q9UCT6
UniProt Entry Name IL1B_HUMAN
Gene Symbol IL1B
GeneID 3553
KEGG hsa:355
String 9606.ENSP00000263341
Molecular Weight Calculated MW: 30 kDa
Observed MW: 31 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interleukin 1 Beta (IL1B) Antibody

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