Interleukin 1 Receptor Type II (IL1R2) Antibody

IL1R2 Antibody is a Rabbit Polyclonal antibody against IL1R2. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Target	Interleukin 1 Receptor Type II (IL1R2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27930 (UniProt, ExPASy)
UniProt Secondary AC	D3DVJ5, Q6LCE6, Q9UE68
UniProt Entry Name	IL1R2_HUMAN
Gene Symbol	IL1R2
GeneID	7850
NCBI Accession	NP_775465.1
KEGG	hsa:7850
String	9606.ENSP00000330959
Molecular Weight	Calculated MW: 45 kDa Observed MW: 45/60-70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interleukin 1 Receptor Type II (IL1R2)

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