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Interleukin 1 Receptor Type II (IL1R2) Antibody
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Catalogue No: abx001557
Price:
US$217.50
(Size: 20 µl)
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IL1R2 Antibody is a Rabbit Polyclonal antibody against IL1R2. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
Research Articles on Interleukin 1 Receptor Type II (IL1R2)
| Target | Interleukin 1 Receptor Type II (IL1R2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to IL1R2. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P27930 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVJ5, Q6LCE6, Q9UE68 |
| UniProt Entry Name | IL1R2_HUMAN |
| Gene Symbol | IL1R2 |
| GeneID | 7850 |
| NCBI Accession | NP_775465.1 |
| KEGG | hsa:7850 |
| String | 9606.ENSP00000330959 |
| Molecular Weight | Calculated MW: 45 kDa Observed MW: 45/60-70 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |