Interleukin 1 Receptor Antagonist (IL1RN) Antibody

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Catalogue No: abx001700
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
IL1RN Antibody is a Rabbit Polyclonal antibody against IL1RN. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Target Interleukin 1 Receptor Antagonist (IL1RN)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-177 of human IL1RA.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18510 (UniProt, ExPASy)
UniProt Secondary AC A8K4G1, Q14628, Q53SC2, Q7RTZ4, Q96GD6, Q9UPC0
UniProt Entry Name IL1RA_HUMAN
Gene Symbol IL1RN
GeneID 3557
OMIM 147679
NCBI Accession NP_776214.1
HGNC 6000
KEGG hsa:3557
Ensembl ENSG00000136689
String 9606.ENSP00000259206
Molecular Weight Calculated MW: 20 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interleukin 1 Receptor Antagonist (IL1RN)


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